RHD Fact Sheet

Quick Facts:

 

  • Known as RHD (Rabbit Hemorrhagic Disease), RCD (Rabbit Calicivirus Disease) or VHD
    (Viral Hemorrhagic Disease)

 

  • It is a highly infectious viral disease that can infect domestic rabbits.
  • It is not known to effect humans or other animals, including cottontails
    and jackrabbits.

Incubation:

 

  • The incubation period is approximately 24 to 48 hours after exposure.

 

Transmission:

  • This virus can be transmitted by contact with infected rabbits, rabbit products
    (including pelts and
    carcasses), contaminated clothing, cages, and feeders.
  • Infected rabbits that may recover become carriers and can shed virus for
    at least 4 weeks.
  • The virus can survive on inanimate objects for up to 3 weeks.

Symptoms:

Young and adult rabbits can die suddenly within 6 – 24 hours of onset of
fever with few clinical signs.

Symptoms may include: –

  • high temperature (2-4 degrees over the
    normal temp)
  • difficulty breathing, lethargy, lack of appetite
  • bleeding from nose/rectum/mouth
  • foamy nasal discharge
  • neurologic signs (excitement, lack of coordination, and
    abnormal head position due to spasms of neck muscles.)
  • The virus can damage the liver, intestines, lymphatic tissue and causes
    terminal massive blood clots.

Treatment:

  • There is no treatment currently available; death rate can range from 50 –
    100 percent in exposed rabbits.

Prevention:

  • There is currently no vaccine legally available in the United
    States.
  • Be cautious and quarantine new rabbits and rabbits coming back from shows
    for at least 5 days.
  • If exposure to the virus is suspected, thoroughly clean then disinfect
    all housing and equipment.

Disinfectant solutions to inactivate the virus:

  • A solution of 10-percent household bleach (exposed a minimum of 10
    minutes)
  • 2-percent 1 Stroke Environ (Steris Corporation, St. Louis, Missouri)
  • 0.5-percent sodium

If you suspect RHD:

  • A necropsy should be done on any rabbit that dies suspiciously
    or showed RHD clinical signs.

US Dept. of Ag, Animal and Plant Health Inspection
Service

Veterinary Services, Emergency Programs
(301) 734-8073 (800) 940-6524
EMOC@ APHIS.USDA.GOV


 

Information from the APHIS
Veterinary Services “Rabbit Calicivirus Disease” Factsheet,
April 2000

Reference – DiGiacomo, R. and Mare, C. (1994). Viral
Diseases In “The Biology of the Laboratory Rabbit.” 2nd Edition

( P. Manning, D. Ringler, C. Newcomer eds.) pp 193-195.
20 Academic Press, San Diego, CA